HORDB

ID: hor006465
Uniprot ID: Q7M3C4
Protein name: Relaxin B chain
Gene name: NA
Organism: Phocoenoides dalli dalli (Dall's porpoise)
Family: Insulin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Phocoenoides dalli (species), Phocoenoides (genus), Phocoenidae (family), Odontoceti (parvorder), Cetacea (infraorder), Whippomorpha (suborder), Artiodactyla (order), Laurasiatheria (superorder), Boreoeutheria , Eutheria , Theria , Mammalia (class), Amniota , Tetrapoda , Dipnotetrapodomorpha , Sarcopterygii (superclass), Euteleostomi , Teleostomi , Gnathostomata , Vertebrata , Craniata (subphylum), Chordata (phylum), Deuterostomia , Bilateria , Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-Q7M3C4-F1.pdb

hor006465_AF2.pdb

hor006465_ESM.pdb

Mass:	407335	Formula:	C154H246N48O44S2
Absent amino acids:	HMPY	Common amino acids:	RV
pI:	8.83	Basic residues:	5
Polar residues:	10	Hydrophobic residues:	12
Hydrophobicity:	-14.19	Boman Index:	-6413
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	81.61
Instability Index:	1396.13	Extinction Coefficient cystines:	11125
Absorbance 280nm:	370.83